What are some risks associated with gentamicin use?

Gentamicin is an aminoglycoside antibiotic that is effective against certain bacterial infections. However, its use is associated with some significant risks, particularly affecting the auditory and renal systems.

Hearing loss is a well-documented risk of gentamicin, as it can affect the inner ear, potentially leading to ototoxicity. This occurs because gentamicin affects the hair cells in the cochlea, which are essential for hearing.

Additionally, gentamicin is known to have nephrotoxic effects, meaning it can harm the kidneys, leading to impaired kidney function. This is particularly concerning in patients with pre-existing kidney conditions, or in those who are taking nephrotoxic medications concurrently.

Understanding these risks is crucial for healthcare providers when prescribing gentamicin, as careful monitoring of kidney function and hearing is needed during treatment to prevent long-term complications.