What is the expected trend of uric acid in infants with respiratory distress syndrome?

In infants with respiratory distress syndrome (RDS), it is expected that uric acid levels will increase. This is primarily due to the stress and hypoxia associated with respiratory distress, which can lead to the breakdown of purines and an increased production of uric acid. Additionally, the impaired renal function often seen in these infants due to their condition can result in decreased clearance of uric acid from the bloodstream, further contributing to elevated uric acid levels. Therefore, in the context of RDS, the physiological responses to stress and the potential for compromised kidney function highlight the reason for the increase in uric acid levels.